Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680373 | 0.86 | MEN1 (0.48) | RAB9AMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL14498671 | 0.86 | TSHR (0.49) | RAB9AMAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL5669641 | 0.86 | POLB (0.54) | RAB9ANPC1TP53SIRT1MEN1 | |
| SCHEMBL13297868 | 0.81 | ALDH1A1 (0.52) | RAB9AMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL1250300 | 0.80 | KMT2A (0.53) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL5688069 | 0.80 | PEPD (0.43) | MAPTSMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL10533529 | 0.79 | F10 (0.44) | RAB9ALMNANPC1KMT2AKDM4E | |
| SCHEMBL7096194 | 0.78 | ABCG2 (0.53) | RAB9AMAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL2892873 | 0.78 | ALDH1A1 (0.45) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL8967579 | 0.77 | MEN1 (0.45) | SMN1; SMN2LMNANPC1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420292-B1 | Stabilizers for use in substantially light-insensitive thermographic recording materials. | AGFA GEVAERT (BE) | 2006-06-28 | — | — | EP | disclosed |
| US-6908731-B2 | Stabilizers for use in substantially light-insensitive thermographic recording materials | AGFA-GEVAERT (BE) | 2005-06-21 | — | — | US | disclosed |