SCHEMBL5688069

SCHEMBL5688069

NC(=O)Nc1ccc(-n2nnnc2S)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.43
KMT2A Q03164 6/20 0.43
MEN1 O00255 5/20 0.43
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
GFER P55789 1/20 0.40
ATM Q13315 1/20 0.39
KIF11 P52732 1/20 0.39
LMNA P02545 1/20 0.39
PTK2 Q05397 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1250300 0.85 KMT2A (0.53) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL2979236 0.83 L3MBTL1 (0.41) KMT2AMEN1ALDH1A1NPC1MAPT
SCHEMBL14498671 0.82 TSHR (0.49) KMT2AMEN1ALDH1A1NPC1MAPT
SCHEMBL2892873 0.82 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1ATMLMNA
SCHEMBL5829189 0.80 RAB9A (0.51) KMT2AMEN1NPC1MAPTLMNA
SCHEMBL13297869 0.80 GAA (0.43) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL14655688 0.80 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1GAAATM
SCHEMBL6835821 0.79 PIP4K2A (0.44) KMT2AMEN1ALDH1A1ATMPTK2
SCHEMBL14498635 0.79 TP53 (0.51) KMT2AMEN1ALDH1A1NPC1GAA
SCHEMBL10959896 0.78 KMT2A (0.53) KMT2AMEN1ALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718679-B1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK CO (US) 2006-02-15 EP disclosed
EP-0772079-B1 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK CO (US) 2002-12-11 EP disclosed
US-5792601-A MODIFYING THE PERFORMANCE PROPERTIES OF THE HIGH CHLORIDE SILVER HALIDE EMULSION BY A COMBINATION OF SILVER BROMIDE ADDITION, IRIDIUM DOPANT INCORPORATION AND ANTIFOGGANT ADDITION EASTMAN KODAK COMPANY (US) 1998-08-11 US disclosed
US-5736310-A SILVER IODOCHLORIDE GRAINS GROWN IN DISPERSING MEDIUM; EMPLOYING GRAINS AS SUBSTRATES FOR FURTHER GRAIN GROWTH EASTMAN KODAK COMPANY (US) 1998-04-07 US disclosed
US-5728516-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-17 US disclosed
US-5726005-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-10 US disclosed
US-5691127-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1997-11-25 US disclosed
US-5631126-A ULTRATHIN GRAINS, IMPROVED FOGGING PROPERTIES, AROMATIC DIHYDROXY SULFONATE, MERCAPTOTETRAZOLE EASTMAN KODAK COMPANY (US) 1997-05-20 US disclosed
US-5629144-A Epitaxially sensitized tabular grain emulsions containing speed/fog mercaptotetrazole enhancing addenda EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0772079-A2 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK COMPANY (US) 1997-05-07 EP disclosed
EP-0718679-A1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
EP-0718676-A1 Photographic print elements containing emulsions of enhanced speed and controlled minimum densities EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed