Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879393 | 0.91 | OPRD1 (0.59) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5632050 | 0.88 | OPRD1 (0.61) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5830266 | 0.87 | OPRD1 (0.62) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829870 | 0.87 | OPRM1 (0.53) | OPRM1OPRD1OPRK1LMNAALDH1A1 | |
| SCHEMBL5828654 | 0.86 | OPRD1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829869 | 0.85 | OPRM1 (0.47) | OPRM1OPRD1OPRK1LMNAALDH1A1 | |
| SCHEMBL5829658 | 0.85 | OPRD1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829602 | 0.83 | OPRD1 (0.46) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829817 | 0.83 | OPRD1 (0.46) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829647 | 0.82 | PARP1 (0.42) | OPRM1OPRD1OPRK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008952-B2 | 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-03-07 | — | — | US | claimed |