Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | UBE2M | P61081 | 3/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879381 | 0.91 | OPRD1 (0.63) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5828654 | 0.90 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5830266 | 0.90 | OPRD1 (0.62) | OPRD1OPRM1OPRK1CHRM3 | |
| SCHEMBL5830258 | 0.87 | OPRD1 (0.56) | OPRD1OPRM1OPRK1CHRM3CYP3A4 | |
| SCHEMBL5830256 | 0.86 | OPRD1 (0.50) | OPRD1OPRM1OPRK1CHRM3CYP3A4 | |
| SCHEMBL5829642 | 0.85 | OPRM1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5829932 | 0.84 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5829612 | 0.84 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5829663 | 0.83 | DRD4 (0.42) | OPRD1OPRM1OPRK1CHRM3CYP3A4 | |
| SCHEMBL5829602 | 0.82 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008952-B2 | 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-03-07 | — | — | US | claimed |