SCHEMBL582974

SCHEMBL582974

Cc1ccc(I)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
ACHE P22303 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559941 0.82 NOTUM (0.31)
SCHEMBL1425995 0.82 NOTUM (0.31)
SCHEMBL30064 0.82 ACHE (0.42) HPGDACHEHTT
SCHEMBL23099880 0.81 CYP1A2 (0.31) ACHE
SCHEMBL18721392 0.81 ACHE (0.31) ACHE
SCHEMBL19882254 0.79 NOTUM (0.40)
SCHEMBL22864465 0.77
SCHEMBL13235153 0.77 NOTUM (0.34)
SCHEMBL615500 0.76
SCHEMBL29373881 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042715-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2026-02-12 US claimed
EP-4565550-A1 FLUORINATION PROCESS Royal College of Surgeons in Ireland (IE) 2025-06-11 EP claimed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO claimed
US-9487470-B2 4-((substituted phenyl) difluoromethyl) phenoxy carboxylic acid derivative, and preparation method and uses thereof ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-11-08 US claimed
US-20150119458-A1 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-04-30 US claimed
EP-2842931-A1 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) 2015-03-04 EP claimed
US-20260042715-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2026-02-12 US disclosed
US-20260042715-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2026-02-12 US disclosed
EP-3227309-B1 CRYSTALLINE DIFUCOSYLLACTOSE GLYCOM AS (DK) 2025-09-24 EP disclosed
EP-4565550-A1 FLUORINATION PROCESS Royal College of Surgeons in Ireland (IE) 2025-06-11 EP disclosed
EP-4565550-A1 FLUORINATION PROCESS Royal College of Surgeons in Ireland (IE) 2025-06-11 EP disclosed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO disclosed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO disclosed
EP-2417144-A1 SYNTHESIS OF 2 ' -O-FUCOSYLLACTOSE Glycom A/S (DK) 2012-02-15 EP disclosed
WO-2010115935-A1 SYNTHESIS OF 2 ' -O-FUCOSYLLACTOSE GLYCOM A/S (DK) 2010-10-14 WO disclosed
US-7732022-B2 Stilbene derivatives, liquid-crystal mixtures and electro-optical displays MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-06-08 US disclosed
CN-100406539-C Cyclohexyl alkynes liquid crystal compounds XIAN MODERN CHEMISTRY RES INST (CN) 2008-07-30 CN disclosed
US-20080149891-A1 STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS MERCK PATENT GESELLSCHAFT (DE) 2008-06-26 US disclosed
CN-1844310-A Cyclohexyl alkynes liquid crystal compounds XIAN MODERN CHEMISTRY RES INST (CN) 2006-10-11 CN disclosed
US-5087764-A Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile Merck Patent Gesellschaft mit beschrankter Hafung (DE) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119458-A1 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF PPARA, PPARG, PPARD HPGD 900/4885ACHE 3204/4885HTT 2123/4885
US-20260042715-A1 FLUORINATION PROCESS XDH, VGF, GTF2F1 HPGD 2578/4885ACHE 3741/4885HTT 3652/4885
US-20080149891-A1 STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS SBDS, LSS, VCL HPGD 1411/4885ACHE 2513/4885HTT 2470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.