Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746450 | 0.88 | OPRM1 (0.37) | OPRM1OPRD1OPRK1MAPTPARP1 | |
| SCHEMBL5879398 | 0.76 | OPRD1 (0.59) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5632123 | 0.74 | OPRD1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5830266 | 0.72 | OPRD1 (0.62) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829609 | 0.72 | OPRD1 (0.46) | OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL5829610 | 0.72 | OPRD1 (0.51) | OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL5829932 | 0.72 | OPRD1 (0.48) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5829602 | 0.72 | OPRD1 (0.46) | OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL5829817 | 0.70 | OPRD1 (0.46) | OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL5828654 | 0.69 | OPRD1 (0.51) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008952-B2 | 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-03-07 | — | — | US | claimed |