SCHEMBL5831443

SCHEMBL5831443

Nc1nc(SCc2ccccc2)c[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 6/20 0.49
▸ NPC1 O15118 4/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ ABL1 P00519 1/20 0.46
▸ RIN1 Q13671 1/20 0.46
▸ POLB P06746 2/20 0.46
▸ ALOX15 P16050 1/20 0.45
▸ PIN1 Q13526 1/20 0.44
▸ LMNA P02545 2/20 0.44
▸ MAPT P10636 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ SCN9A Q15858 1/20 0.44
▸ HSP90AA1 P07900 1/20 0.44
▸ MPO P05164 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ CDC7 O00311 1/20 0.41
▸ DBF4 Q9UBU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29464867 0.71 RAB9A (0.56) RAB9ANPC1SMN1; SMN2ABL1RIN1
SCHEMBL8979785 0.71 RAB9A (0.56) RAB9ANPC1SMN1; SMN2ABL1RIN1
Hydrochloric Acid SCHEMBL10563346 0.70 RAB9A (0.54) RAB9ANPC1SMN1; SMN2ABL1RIN1
SCHEMBL6582698 0.69 RAB9A (0.42) RAB9ANPC1SMN1; SMN2ABL1RIN1
SCHEMBL6207563 0.69 RECQL (0.71) RAB9ANPC1SMN1; SMN2ALOX15LMNA
SCHEMBL3499813 0.68 RAB9A (0.56) RAB9ANPC1SMN1; SMN2POLBALOX15
SCHEMBL6760838 0.68 ABL1 (0.45) RAB9ANPC1SMN1; SMN2ABL1RIN1
SCHEMBL308391 0.67 KMT2A (0.55) RAB9ANPC1SMN1; SMN2POLBALOX15
SCHEMBL10754261 0.67 RAB9A (0.50) RAB9ANPC1SMN1; SMN2POLBALOX15
SCHEMBL7164011 0.67 ABL1 (0.44) RAB9ANPC1SMN1; SMN2ABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060169395-A1 Assembled structures of carbon tubes and method for making the same HAN CHIEN-CHUNG 2006-08-03 — — US disclosed
US-7034100-B2 Heterogeneous reaction method for preparing functionalized polyanilines NATIONAL TSING HUA UNIVERSITY (TW) 2006-04-25 — — US disclosed
CN-1590287-A Carbon tube composite structure and preparation method thereof HAN CHIEN CHUNG (CN) 2005-03-09 — — CN disclosed
US-20030224132-A1 Assembled structures of carbon tubes and method for making the same HAN CHIEN-CHUNG (TW) 2003-12-04 — — US disclosed
US-6602567-B2 Open ended hollow devices of controlled thickness and appreciate length length; uniformity NATIONAL TSING HUA UNIVERSITY (TW) 2003-08-05 — — US disclosed
US-6506323-B1 Coating natural or synthetic fiber; thermal, solvent or chemical removal of fiber; carbonizing coating NATIONAL TSING HUA UNIVERSITY (TW) 2003-01-14 — — US disclosed
US-20020081275-A1 Heterogeneous reaction method for preparing functionalized polyanilines NATIONAL TSING HUA UNIVERSITY (TW) 2002-06-27 — — US disclosed
US-6380346-B1 HIGH SOLUBILITY AND/OR HIGH PROCESSIBILITY; TREATMENT WITH A SOLUTION OF REACTIVE CHEMICAL REAGENT(S), E.G. MERCAPTAN, IN A SELECTED SOLVENT; FUNCTIONALIZING THE SOLID POLYANILINE AND TRANSFORMING THE BACKBONE INTO A MORE REDUCED FORM NATIONAL TSING HUA UNIVERSITY (TW) 2002-04-30 — — US disclosed
US-20020048644-A1 Method for making micrometer-sized carbon tubes NATIONAL TSING HUA UNIVERSITY (TW) 2002-04-25 — — US disclosed
EP-0623159-B1 CONJUGATED POLYMER PAINT FORMULATIONS WHICH PROVIDE CORROSION RESISTANCE TO METAL SURFACES ZIPPERLING KESSLER & CO (DE) 1999-06-16 — — EP disclosed
US-5225495-A Polyanilines Stewart, II, Richard C. (US) 1993-07-06 — — US disclosed
WO-1993005519-A1 SOLUBILITY MODIFICATION OF CONDUCTIVE CONJUGATED BACKBONE POLYMERS VIA THE DOPANT MOIETIES ALLIED-SIGNAL INC. (US) 1993-03-18 — — WO disclosed
US-5171478-A Doping with organic acids or salts; electroconductive ALLIED-SIGNAL INC. (US) 1992-12-15 — — US disclosed
US-5160457-A Dopes, fibers, films, moldings, sheets ALLIED-SIGNAL INC. (US) 1992-11-03 — — US disclosed
WO-1992011644-A1 METHOD OF PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN SOLVENT MIXTURES ALLIED-SIGNAL INC. (US) 1992-07-09 — — WO disclosed
EP-0461182-A1 THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE. ALLIED SIGNAL INC (US) 1991-12-18 — — EP disclosed
US-5069820-A DOPED WITH ORGANIC SULFONATE ALLIED-SIGNAL INC. (US) 1991-12-03 — — US disclosed
WO-1990010297-A1 THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE ALLIED-SIGNAL INC. (US) 1990-09-07 — — WO disclosed
EP-0380517-A1 THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE. ALLIED SIGNAL INC (US) 1990-08-08 — — EP disclosed
WO-1989001694-A1 THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE ALLIED-SIGNAL INC. (US) 1989-02-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020081275-A1 Heterogeneous reaction method for preparing functionalized polyanilines PARG, TET2, ROS1 RAB9A 3555/4885NPC1 4844/4885SMN1; SMN2 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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