Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164011 | 0.98 | ABL1 (0.44) | ABL1RIN1HSD17B10RAB9ANPC1 | |
| SCHEMBL4311271 | 0.90 | POLB (0.36) | ABL1RIN1HSD17B10RAB9ANPC1 | |
| SCHEMBL8621794 | 0.84 | CYP1A2 (0.43) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL30883908 | 0.76 | KMT2A (0.50) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29699407 | 0.75 | CYP1A2 (0.48) | SMN1; SMN2KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6988242 | 0.72 | RAB9A (0.48) | ABL1RIN1HSD17B10RAB9ANPC1 | |
| SCHEMBL23457494 | 0.72 | CYP1A2 (0.37) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6839048 | 0.71 | HPGD (0.40) | HSD17B10SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL2705829 | 0.70 | USP2 (0.31) | — | |
| SCHEMBL8442599 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717266-A2 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therapeutics Incorporated (US) | 2026-04-01 | — | — | EP | disclosed |
| US-20250248973-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. | 2025-08-07 | — | — | US | disclosed |
| EP-4577536-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | Hotspot Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20250099457-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | US | disclosed |
| US-12226412-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| EP-4504179-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | Corbus Pharmaceuticals, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| US-20250034140-A1 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therpeutics, Inc. (US) | 2025-01-30 | — | — | US | disclosed |
| CN-119325378-A | Cannabinoid receptor 1 antagonists/inverse agonists and uses thereof | 柯巴斯医药有限公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20240400502-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | UNIV QUEENSLAND (AU) | 2024-12-05 | — | — | US | disclosed |
| US-12139486-B2 | Octahydro fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| US-8859774-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859774-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| WO-2014140310-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-09-18 | — | — | WO | disclosed |
| US-20140275086-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275087-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140038926-A1 | Heteroaryl-Ketone Fused Azadecalin Glucocorticoid Receptor Modulators | CORCEPT THERAPEUTICS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140038926-A1 | Heteroaryl-Ketone Fused Azadecalin Glucocorticoid Receptor Modulators | CORCEPT THERAPEUTICS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140038926-A1 | Heteroaryl-Ketone Fused Azadecalin Glucocorticoid Receptor Modulators | CORCEPT THERAPEUTICS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2013177559-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| US-6828070-B2 | Heat sensitive element | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250248973-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | CNR1, CNR2, GPR119 | ABL1 3566/4885RIN1 1426/4885HSD17B10 1446/4885 |
| US-20250099457-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, GRIN3A, NR3C2 | ABL1 4203/4885RIN1 2281/4885HSD17B10 301/4885 |
| US-20140275086-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | SLC6A7, GFPT1, SUGT1 | ABL1 1135/4885RIN1 2674/4885HSD17B10 1043/4885 |
| US-20250034140-A1 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, NR5A1 | ABL1 3966/4885RIN1 3263/4885HSD17B10 762/4885 |
| US-20240400502-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, PYCARD, IAPP | ABL1 4714/4885RIN1 1929/4885HSD17B10 2945/4885 |
| US-20140038926-A1 | Heteroaryl-Ketone Fused Azadecalin Glucocorticoid Receptor Modulators | NR3C1, NR3C2, NR5A1 | ABL1 2153/4885RIN1 2929/4885HSD17B10 132/4885 |
| US-12226412-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | NR3C1, GRIN3A, NR3C2 | ABL1 4203/4885RIN1 2281/4885HSD17B10 301/4885 |
| US-20140275087-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | SLC6A7, GFPT1, SUGT1 | ABL1 1135/4885RIN1 2674/4885HSD17B10 1043/4885 |
| US-12139486-B2 | Octahydro fused azadecalin glucocorticoid receptor modulators | NR3C1, NR3C2, NR5A1 | ABL1 3966/4885RIN1 3263/4885HSD17B10 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.