Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583036 | 0.75 | CA12 (0.56) | RAB9ACA12CA1CA2CA4 | |
| SCHEMBL583044 | 0.75 | THRB (0.43) | ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL19474968 | 0.75 | SYK (0.47) | RAB9ASMN1; SMN2PKMMAPTNPC1 | |
| SCHEMBL583233 | 0.74 | KMT2A (0.54) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL8893668 | 0.73 | CA12 (0.62) | SMN1; SMN2MAPTALDH1A1APPCA12 | |
| SCHEMBL10053685 | 0.72 | GAA (0.45) | RAB9ASMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL16471789 | 0.70 | TACR2 (0.37) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16459003 | 0.70 | TACR2 (0.52) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL30416387 | 0.70 | HTR1A (0.74) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL791853 | 0.70 | HTR1A (0.74) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213666-B1 | LIGUSTRAZINE AROMATIC ACID ETHER DERIVATIVE, ITS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION | LI JIAMING (CN) | 2012-02-15 | — | — | EP | claimed |