Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944531 | 0.89 | ATM (0.41) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL143450 | 0.85 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1718931 | 0.83 | ATM (0.44) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL49180 | 0.83 | ATM (0.44) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9227871 | 0.82 | TSHR (0.53) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL395579 | 0.82 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL11127827 | 0.82 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL332045 | 0.81 | ATM (0.48) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL63718 | 0.81 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL6652514 | 0.81 | ATM (0.42) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030259-B2 | Process for the preparation of silicone compounds | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050256330-A1 | Process for the preparation of silicone compounds | DOW TORAY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1472264-B1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1472264-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064436-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |
| US-6399212-B1 | COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE | NIPPON SHEET GLASS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1094090-A2 | Silicon dioxide-coated polyolefin resin and process for its production | NIPPON SHEET GLASS CO. LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256330-A1 | Process for the preparation of silicone compounds | ADH1C, ACMSD, SORD | ATM 726/4885HCAR2 1021/4885MAPT 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.