Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | HTR1D | P28221 | 7/20 | 0.49 |
| ▸ | HTR1B | P28222 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | IGF1R | P08069 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115183 | 0.95 | HTR1A (0.52) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL12720754 | 0.75 | ADRB2 (0.71) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL2539667 | 0.75 | SCN9A (0.50) | EGFRIGF1RFLT4KDRADRB2 | |
| SCHEMBL2540215 | 0.73 | ADRB2 (0.47) | HTR1AHTR1DHTR1BCYP1A2CYP2C9 | |
| Oxalic Acid SCHEMBL3115180 | 0.72 | HTR1B (0.87) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| Oxalic Acid SCHEMBL8628241 | 0.72 | HTR1B (0.87) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL7094588 | 0.70 | ADRB2 (0.60) | HTR1AHTR1DHTR1BMAPTCYP1A2 | |
| SCHEMBL6830010 | 0.70 | ADRB2 (0.58) | HTR1AHTR1DHTR1BMAPTCYP1A2 | |
| SCHEMBL15319614 | 0.67 | HTR2A (0.51) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL21523197 | 0.66 | HTR2A (0.50) | HTR1AHTR1DHTR1BMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020173511-A1 | Serotonergic compositions and methods for treatment of mild cognitive impairment | WURTMAN RICHARD J (US) | 2002-11-21 | — | — | US | claimed |
| WO-2002038142-A2 | SEROTONERGIC COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-05-16 | — | — | WO | claimed |
| US-20060079447-A1 | Stabilized A-beta protofibrillar aggregates | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-04-13 | — | — | US | disclosed |
| US-7013836-B1 | Enhancing maturation of oocytes in bivalves | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-03-21 | — | — | US | disclosed |
| US-20020173511-A1 | Serotonergic compositions and methods for treatment of mild cognitive impairment | WURTMAN RICHARD J (US) | 2002-11-21 | — | — | US | disclosed |
| WO-2002038142-A2 | SEROTONERGIC COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-05-16 | — | — | WO | disclosed |