Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396854 | 0.84 | HTR3A (0.45) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2133059 | 0.76 | NR4A2 (0.54) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6665214 | 0.76 | KDM4E (0.43) | CYP2A6AHRLMNACYP1A2MAPT | |
| SCHEMBL30506415 | 0.76 | NR4A2 (0.54) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7608692 | 0.75 | NR4A2 (0.52) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23779362 | 0.73 | NR4A2 (0.50) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL462171 | 0.73 | BACE1 (0.58) | NR4A2PIK3CGLMNACYP1A2MAPT | |
| SCHEMBL30572491 | 0.73 | ALDH1A1 (0.50) | CYP1A2ALOX15PDGFRBPDGFRA | |
| SCHEMBL14720338 | 0.73 | NR4A2 (0.50) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27390744 | 0.73 | NR4A2 (0.50) | NR4A2HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022855-B2 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |