Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3291942 | 0.97 | SIGMAR1 (0.44) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| Hydrochloric Acid SCHEMBL3291945 | 0.97 | SIGMAR1 (0.44) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL4618223 | 0.97 | SIGMAR1 (0.46) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL4618229 | 0.97 | SIGMAR1 (0.46) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL30635011 | 0.97 | SIGMAR1 (0.46) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL5693660 | 0.95 | SIGMAR1 (0.45) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL5586865 | 0.95 | SIGMAR1 (0.45) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| Hydrochloric Acid SCHEMBL8091098 | 0.94 | NOS3 (0.46) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL5833498 | 0.91 | SIGMAR1 (0.42) | SIGMAR1NOS3NOS1NOS2GRIN2D | |
| SCHEMBL14792876 | 0.90 | SIGMAR1 (0.41) | SIGMAR1NOS3NOS1NOS2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001964-B2 | Selective isomerization and linear dimerization of olefins using cobalt catalysts | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2006-02-21 | — | — | US | disclosed |
| US-6911505-B2 | Selective isomerization and linear dimerization of olefins using cobalt catalysts | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040068154-A1 | Selective isomerization and linear dimerization of olefins using cobalt catalysts | CHEVRON PHILLIPS CHEMICAL COMPANY | 2004-04-08 | — | — | US | disclosed |
| US-20040068072-A1 | Selective isomerization and linear dimerization of olefins using cobalt catalysts | CHEVRON PHILLIPS CHEMICAL COMPANY | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068154-A1 | Selective isomerization and linear dimerization of olefins using cobalt catalysts | PPOX, OXER1, OCIAD1 | SLC6A2 4153/4885SIGMAR1 1112/4885NOS3 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.