SCHEMBL58345

SCHEMBL58345

CCOC(=O)c1ccc(N(CCCO)CCCO)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAOA P21397 1/20 0.51
RAB9A P51151 7/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
NPC1 O15118 4/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
MAPT P10636 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8119057 0.95 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL23961165 0.91 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL2388270 0.90 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8602388 0.89 ESR1 (0.54) CA12CA1CA2CA7CA9
SCHEMBL7152467 0.88 ALDH1A1 (0.55) ESR1LMNACYP1A2CYP3A4MAOA
SCHEMBL8726492 0.84 RAB9A (0.50) CA12CA1CA2CA7CA9
SCHEMBL20190404 0.83 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL7460977 0.83 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL65692 0.82 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL8376259 0.80 ESR1 (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
US-20250332079-A1 TOPICAL SUNSCREEN CONCEPT MATRIX SOLUTIONS 2025-10-30 US claimed
EP-4093514-B1 AQUEOUS SUNCASE FORMULATION BASED ON SULFATED A CRYSTALLINE CELLULOSE SPF BOOSTER DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-06 EP claimed
US-12214067-B2 Oil-in-water emulsion sunscreen composition ISP INVESTMENTS INC. (US) 2025-02-04 US claimed
EP-3894017-B1 POLYMER BLEND FOR PERSONAL CARE FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-28 EP claimed
US-20230034183-A1 AQUEOUS SUNCARE FORMULATION DOW GLOBAL TECHNOLOGIES LLC 2023-02-02 US claimed
EP-3893836-B1 PERSONAL CARE FORMULATION COMPRISING A MULTISTAGE POLYMER WITH A CARBOSILOXANE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-28 EP claimed
US-20220387290-A1 SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-12-08 US claimed
US-20220125701-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-04-28 US claimed
EP-0552289-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES INC. (US) 1993-07-28 EP claimed
WO-1992005769-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES, INC. (US) 1992-04-16 WO claimed
WO-1992005768-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1992-04-16 WO claimed
US-5100918-A Prevention or treatment of sunburn using the S(+) isomer of ibuprofen STERLING DRUG, INC. (US) 1992-03-31 US claimed
US-4731242-A Waterproof sunscreen compositions PALINCZAR VICTOR (US) 1988-03-15 US claimed
US-4707354-A Mature skin treatment and protectant compositions and methods of using same ALPEN TAU, INC. (US) 1987-11-17 US claimed
US-4699779-A Waterproof sunscreen compositions PALINCZAR VICTOR 1987-10-13 US claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed
US-4671955-A ETHYL HYDROXYETHYL CELLULOSE AND AN ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR 1987-06-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332079-A1 TOPICAL SUNSCREEN SUN2, CYP51A1, DSG1 CA12 4644/4885CA1 4864/4885CA2 4487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.