SCHEMBL5835461

SCHEMBL5835461

C=CCc1cc(C(=O)O)nc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.51
MGAM O43451 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
IGFBP5 P24593 2/20 0.42
IGFBP3 P17936 1/20 0.42
PDE10A Q9Y233 2/20 0.41
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27928660 0.82 ALOX15 (0.58) ALOX15MGAMALDH1A1HPGDHSD17B10
SCHEMBL8852131 0.81 MGAM (0.49) ALOX15MGAMALDH1A1HPGDHSD17B10
SCHEMBL30744791 0.80 ALOX15 (0.61) ALOX15MGAMALDH1A1HPGDHSD17B10
SCHEMBL472912 0.79 MEN1 (0.42) ALOX15ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL30744751 0.78 KDM4E (0.59) ALOX15MGAMALDH1A1HPGDHSD17B10
SCHEMBL6604473 0.78 ALOX15 (0.54) ALOX15MGAMALDH1A1HPGDHSD17B10
SCHEMBL15648557 0.77 KDM4E (0.38) ALDH1A1HPGDHSD17B10KDM4ELMNA
SCHEMBL16836561 0.76 BACE1 (0.51) ALDH1A1HPGDHSD17B10KDM4ELMNA
SCHEMBL27829330 0.75 PTPN1 (0.45) ALOX15ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL30420748 0.75 ALOX15 (0.63) ALOX15MGAMALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed