Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.43 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744791 | 0.90 | ALOX15 (0.61) | KDM4EALOX15ALDH1A1HPGDMGAM | |
| SCHEMBL28623461 | 0.89 | ALOX15 (0.54) | KDM4EALOX15ALDH1A1HPGDGAA | |
| SCHEMBL11038698 | 0.88 | KDM4E (0.53) | KDM4EALOX15ALDH1A1HPGDGAA | |
| SCHEMBL27928660 | 0.84 | ALOX15 (0.58) | KDM4EALOX15ALDH1A1HPGDMGAM | |
| SCHEMBL6604473 | 0.83 | ALOX15 (0.54) | KDM4EALOX15ALDH1A1HPGDMGAM | |
| SCHEMBL30420748 | 0.81 | ALOX15 (0.63) | KDM4EALOX15ALDH1A1HPGDMGAM | |
| SCHEMBL30438333 | 0.80 | ALOX15 (0.54) | KDM4EALOX15ALDH1A1HPGDMGAM | |
| SCHEMBL30744928 | 0.79 | GRM2 (0.43) | KDM4EALOX15IGFBP3IGFBP5 | |
| SCHEMBL4239380 | 0.78 | KDM4E (0.49) | KDM4EALOX15ALDH1A1HPGDGAA | |
| SCHEMBL5835461 | 0.78 | ALOX15 (0.51) | KDM4EALOX15ALDH1A1HPGDMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |