Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | IGFBP5 | P24593 | 2/20 | 0.47 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744791 | 0.87 | ALOX15 (0.61) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL6604473 | 0.84 | ALOX15 (0.54) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL30744751 | 0.84 | KDM4E (0.59) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL5835461 | 0.82 | ALOX15 (0.51) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL30420748 | 0.82 | ALOX15 (0.63) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL6080381 | 0.81 | KDM4E (0.42) | ALOX15IGFBP5IGFBP3KDM4ELMNA | |
| SCHEMBL28623461 | 0.80 | ALOX15 (0.54) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9602865 | 0.80 | ALOX15 (0.50) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL30438333 | 0.80 | ALOX15 (0.54) | ALOX15MGAMALDH1A1HPGDHSD17B10 | |
| SCHEMBL2114841 | 0.80 | GRM2 (0.61) | ALOX15MGAMALDH1A1HPGDPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |
| CN-105777870-A | Novel thiostrepton analogue and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2016-07-20 | — | — | CN | disclosed |
| CN-103205470-A | Functions and application of short chain dehydrogenase TsrU | SHANGHAI INST ORGANIC CHEM | 2013-07-17 | — | — | CN | disclosed |