Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.47 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594884 | 0.88 | PLA2G2A (0.46) | ALOX15NPC1RAB9A | |
| SCHEMBL27928660 | 0.84 | ALOX15 (0.58) | ALOX15MGAMIGFBP3IGFBP5ALDH1A1 | |
| SCHEMBL30744751 | 0.83 | KDM4E (0.59) | ALOX15MGAMIGFBP3IGFBP5ALDH1A1 | |
| SCHEMBL30744791 | 0.83 | ALOX15 (0.61) | ALOX15MGAMIGFBP3IGFBP5ALDH1A1 | |
| SCHEMBL6079288 | 0.82 | KDM4E (0.51) | IGFBP3IGFBP5CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6597624 | 0.81 | KDM4E (0.41) | IGFBP5CSNK2A2CSNK2BCSNK2A1KDM4E | |
| Hydrochloric Acid SCHEMBL6080175 | 0.80 | KDM4E (0.40) | IGFBP5ALDH1A1HPGDHSD17B10CSNK2A2 | |
| SCHEMBL28623461 | 0.80 | ALOX15 (0.54) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL31389295 | 0.79 | ALOX15 (0.61) | ALOX15ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL11038698 | 0.78 | KDM4E (0.53) | ALOX15ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |