SCHEMBL5835751

SCHEMBL5835751

C=C(CC)C(=O)OOC(C)OCCCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ATM Q13315 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899020 0.83 LMNA (0.39)
SCHEMBL28258557 0.80 NAAA (0.41) TSHRHPGDALDH1A1ATMNAAA
SCHEMBL9474690 0.78 AKR1C3 (0.41) HPGD
SCHEMBL2957621 0.78 ALDH1A1 (0.47) TSHRHPGDALDH1A1ATM
SCHEMBL6378508 0.78 TSHR (0.31) TSHR
SCHEMBL28167057 0.77 LMNA (0.34)
SCHEMBL1947721 0.76 ALDH1A1 (0.45) TSHRHPGDALDH1A1ATM
SCHEMBL14335765 0.75 TSHR (0.40) TSHRHPGDALDH1A1ATMNAAA
SCHEMBL11572223 0.75 TSHR (0.53) TSHRHPGDALDH1A1ATM
SCHEMBL28402676 0.75 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1408059-B1 Latex and its preparation SYNTHOMER DEUTSCHLAND GMBH (DE) 2014-04-23 EP disclosed
US-7101927-B2 Latex obtainable by a gradient regime reaction STERNAGEL FLEISCHER GODEMEYER & PARTNER (DE) 2006-09-05 US disclosed
US-20040072945-A1 Latex and its preparation STERNAGEL FLEISCHER GODEMEYER & PARTNER (DE) 2004-04-15 US disclosed
EP-1408059-A1 Latex and its preparation Polymer Latex GmbH & Co. KG (DE) 2004-04-14 EP disclosed