Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 6/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835751 | 0.78 | TSHR (0.34) | HPGD | |
| SCHEMBL4901097 | 0.76 | LMNA (0.44) | NPC1RAB9AMEN1KMT2APPARG | |
| SCHEMBL3506182 | 0.73 | MEN1 (0.44) | NPC1RAB9AMEN1KMT2APTGES | |
| SCHEMBL16009093 | 0.72 | HDAC3 (0.48) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL16672870 | 0.71 | CTSK (0.48) | NPC1RAB9AHPGDHDAC3PTGES | |
| SCHEMBL7299043 | 0.70 | MAPT (0.53) | MEN1KMT2AHDAC3ALOX5FFAR1 | |
| SCHEMBL3997663 | 0.70 | ALDH1A1 (0.53) | NPC1RAB9AALOX5FFAR1TDP1 | |
| SCHEMBL11201910 | 0.69 | SMN1; SMN2 (0.51) | NPC1RAB9AKMT2AHPGDHDAC3 | |
| SCHEMBL6131026 | 0.69 | ALDH1A1 (0.42) | HPGDHDAC3PTGESALOX5PPARG | |
| SCHEMBL28389780 | 0.69 | TSHR (0.59) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252427-A | Polymer having pendant acid labile groups and free acid groups, substance that forms acid upon exposure to actinic ratiation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-12 | — | — | US | claimed |
| US-5252427-A | Polymer having pendant acid labile groups and free acid groups, substance that forms acid upon exposure to actinic ratiation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |