Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869647 | 0.98 | SIGMAR1 (0.41) | SIGMAR1POLBCA1CA2CHRNA7 | |
| SCHEMBL21314162 | 0.92 | SIGMAR1 (0.37) | SIGMAR1POLBCA1CA2CHRNA7 | |
| Hydrochloric Acid SCHEMBL6115226 | 0.90 | CA1 (0.40) | POLBCA1CA2 | |
| SCHEMBL21314160 | 0.89 | POLB (0.40) | SIGMAR1POLBCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL925005 | 0.88 | CA1 (0.40) | POLBCA1CA2 | |
| SCHEMBL6115185 | 0.83 | CA1 (0.37) | POLBCA1CA2 | |
| SCHEMBL17316663 | 0.80 | MEN1 (0.54) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL9664482 | 0.80 | IGF1R (0.41) | — | |
| Hydrochloric Acid SCHEMBL382999 | 0.80 | ALDH1A1 (0.46) | POLBCA1CA2 | |
| SCHEMBL4546758 | 0.79 | EEF2K (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312852-B2 | Method for preparing graft copolymer complex, graft copolymer complex, and thermoplastic resin composition comprising graft copolymer complex | LG CHEM, LTD. (KR) | 2022-04-26 | — | — | US | disclosed |
| EP-3533810-B1 | METHOD FOR PREPARING GRAFT COPOLYMER COMPLEX, GRAFT COPOLYMER COMPLEX, AND THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER COMPLEX | LG CHEMICAL LTD (KR) | 2021-04-21 | — | — | EP | disclosed |
| EP-3533810-A1 | METHOD FOR PRODUCING GRAFT COPOLYMER COMPOSITE, GRAFT COPOLYMER COMPOSITE, AND THERMOPLASTIC RESIN COMPOSITION INCLUDING SAME | LG Chem, Ltd. (KR) | 2019-09-04 | — | — | EP | disclosed |
| US-7005282-B2 | Enzymes coated with ionic liquid | POSCO AND POSTECH FOUNDATION (KR) | 2006-02-28 | — | — | US | disclosed |
| EP-1468083-A1 | ENZYMES COATED WITH IONIC LIQUID | Posco (KR) | 2004-10-20 | — | — | EP | disclosed |
| CN-1498268-A | Enzymes coated with ionic liquid | POSCO公司 | 2004-05-19 | — | — | CN | disclosed |
| US-20040087462-A1 | Enzymes cooated with ionic liquid | POSCO (KR) | 2004-05-06 | — | — | US | disclosed |
| WO-2003057871-A1 | ENZYMES COATED WITH IONIC LIQUID | POSCO (KR) | 2003-07-17 | — | — | WO | disclosed |