SCHEMBL5836075

SCHEMBL5836075

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837290 0.89
SCHEMBL7597032 0.87 ALOX15 (0.31)
SCHEMBL137885 0.86 ENPP3 (0.32) ALDH1A1
SCHEMBL139133 0.86
SCHEMBL219287 0.85
SCHEMBL6447484 0.85 ENPP3 (0.34)
SCHEMBL5836286 0.84
SCHEMBL8679172 0.84 P2RX7 (0.38) KDM4EALDH1A1
SCHEMBL138153 0.84 ALOX15 (0.30)
SCHEMBL6446037 0.83 MAPT (0.33) KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
US-5770752-A Process for reducing the concentration of by-products in product mixtures TARGOR GMBH (DE) 1998-06-23 US disclosed