Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.63 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836942 | 0.84 | MAPT (0.60) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL5836186 | 0.83 | MAPT (0.68) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL1986101 | 0.80 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL156355 | 0.80 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL6608042 | 0.80 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9014036 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL33852 | 0.78 | ALDH1A1 (0.91) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL5836614 | 0.78 | GAA (0.49) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1153999 | 0.76 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL7130594 | 0.75 | ALDH1A1 (0.83) | ALDH1A1MAPTGAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | claimed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | disclosed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | KRT18, CDC73, VIM | ALDH1A1 1327/4885MAPT 1211/4885GAA 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.