SCHEMBL5837064

SCHEMBL5837064

CC1=Cc2c(-c3cc(C)cc(C)c3)cccc2C1[Si](C)(C)C1C(C)=Cc2c(-c3cc(C)cc(C)c3)cccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1451902 0.92
SCHEMBL1452889 0.92 NPC1 (0.30)
SCHEMBL15827902 0.90 ADORA3 (0.30)
SCHEMBL6648868 0.90 CHEK1 (0.40)
SCHEMBL1454590 0.86 ADORA3 (0.33)
SCHEMBL15827899 0.86 ADORA3 (0.30)
SCHEMBL5838399 0.85 PDK2 (0.31)
SCHEMBL15827900 0.85 ADORA3 (0.30)
SCHEMBL61908 0.84 PDCD1 (0.34) BRD4
SCHEMBL29366427 0.84 PDCD1 (0.34) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
EP-1015463-B1 METHOD FOR PRODUCING METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2002-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN BRD4 1783/4885CREBBP 3276/4885
US-20190308995-A1 CATALYSTS SIGMAR1, H1-2, CBR1 BRD4 1701/4885CREBBP 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.