Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5917460 | 1.00 | ACE (0.49) | ACEMMEXIAP | |
| SCHEMBL5377148 | 0.90 | ACE (0.60) | ACEMME | |
| SCHEMBL5568859 | 0.87 | DRD2 (0.45) | ACE | |
| SCHEMBL13895644 | 0.87 | ACE (0.53) | ACEMMEXIAP | |
| SCHEMBL27643156 | 0.87 | ACE (0.53) | ACEMMEXIAP | |
| SCHEMBL5563609 | 0.85 | DRD2 (0.41) | ACEMME | |
| SCHEMBL10752343 | 0.82 | HDAC8 (0.50) | ACE | |
| SCHEMBL27705655 | 0.82 | HDAC8 (0.50) | ACE | |
| SCHEMBL2827018 | 0.82 | DRD2 (0.51) | — | |
| SCHEMBL2827020 | 0.82 | DRD2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060842-B2 | Method for synthesis of (2S, 3aS, 7aS)-1-{(S)-alanyl}-octahydro-1H -indole-2-carboxylic acid derivatives and use for synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2006-06-13 | — | — | US | disclosed |
| US-20040198988-A1 | Catalytic hydrogenation; crystallization; isolation | LES LABORATOIRES SERVIER (FR) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198988-A1 | Catalytic hydrogenation; crystallization; isolation | REN, ACE, PEPD | ACE 2/4885MME 199/4885XIAP 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.