Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643156 | 1.00 | ACE (0.53) | ACEMMECTSLXIAP | |
| SCHEMBL5917460 | 0.87 | ACE (0.49) | ACEMMEXIAP | |
| SCHEMBL5837686 | 0.87 | ACE (0.49) | ACEMMEXIAP | |
| SCHEMBL5377148 | 0.85 | ACE (0.60) | ACEMME | |
| SCHEMBL10842684 | 0.84 | ACE (0.53) | ACECTSL | |
| SCHEMBL8834681 | 0.83 | KLK5 (0.51) | ACECTSL | |
| SCHEMBL5350591 | 0.82 | CTSL (0.52) | ACECTSL | |
| SCHEMBL16466358 | 0.80 | XIAP (0.52) | ACEXIAP | |
| SCHEMBL16466356 | 0.80 | XIAP (0.52) | ACEXIAP | |
| SCHEMBL9699149 | 0.79 | PREP (0.61) | ACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521566-B2 | Process for preparation of perindopril and salts thereof | LES LABORATOIRES SERVIER (FR) | 2009-04-21 | — | — | US | disclosed |
| US-7456296-B2 | Method for preparation of crystalline perindopril erbumine | LUPIN LTD (IN) | 2008-11-25 | — | — | US | disclosed |