Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A known ✓ | Q14432 | 2/20 | 0.43 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 6/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764074 | 0.91 | TYMS (0.55) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL20699854 | 0.82 | LPAR3 (0.50) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL1260815 | 0.82 | LPAR3 (0.50) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL11630697 | 0.80 | LPAR3 (0.48) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL19211969 | 0.78 | GRM4 (0.52) | LMNACYP3A4NFKB1BLMPMP22 | |
| Ethylenediamine SCHEMBL69119 | 0.78 | LMNA (0.78) | LMNACYP3A4NFKB1BLMPMP22 | |
| Ethylenediamine SCHEMBL10933099 | 0.78 | LMNA (0.78) | LMNACYP3A4NFKB1BLMPMP22 | |
| Ethylenediamine SCHEMBL4154009 | 0.76 | LMNA (0.74) | LMNACYP3A4NFKB1BLMPMP22 | |
| Ethylenediamine SCHEMBL5157252 | 0.76 | LMNA (0.74) | LMNACYP3A4NFKB1BLMPMP22 | |
| Ethylenediamine SCHEMBL15053407 | 0.76 | LMNA (0.74) | LMNACYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203523-B1 | ALKALINE HYDROXIDE-CONTAINING COMPOUNDS IN MELTED BLOCK FORM FOR MACHINE DISH-WASHING, AND PROCESS FOR THEIR PREPARATION | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-01-23 | — | — | EP | claimed |
| US-4569838-A | GELLING AGENT OF IOTA-CARRAGEENAN AND XANTHAN GUM MIXTURE WITH PHOSPHONATE ANTINUCLEATING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 1986-02-11 | — | — | US | claimed |
| CN-112726126-B | Scale inhibition washing drum for clothes treatment device and preparation method thereof | 云米互联科技(广东)有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-112726133-B | Scale inhibition outer cylinder for clothes treatment device and preparation method thereof | 云米互联科技(广东)有限公司 | 2023-06-13 | — | — | CN | disclosed |
| US-11208619-B2 | Unit dose detergent products with effect on protein stains | Henkel IP & Holding GmbH (DE) | 2021-12-28 | — | — | US | disclosed |
| US-11154625-B2 | Fucoidans as ligands for the diagnosis of degenerative pathologies | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2021-10-26 | — | — | US | disclosed |
| US-20210054317-A1 | Unit Dose Detergent Products With Effect On Protein Stains | Henkel IP & Holding GmbH (DE) | 2021-02-25 | — | — | US | disclosed |
| EP-3156078-B1 | FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES | INST NAT SANTE RECH MED (FR) | 2020-03-04 | — | — | EP | disclosed |
| EP-3156078-A1 | FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES | UNIVERSITE PARIS-NORD 13 (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2416806-B1 | FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES | UNIVERSITÉ PARIS 13 (FR) | 2016-12-14 | — | — | EP | disclosed |
| US-20150337308-A1 | MATRIX METALLOPROTEINASE 9 (MMP-9) APTAMER AND USES THEREOF | CHU DE BORDEAUX (FR) | 2015-11-26 | — | — | US | disclosed |
| WO-2013153138-A1 | MATRIX METALLOPROTEINASE 9 (MMP-9) APTAMER AND USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-10-17 | — | — | WO | disclosed |
| US-20120183475-A1 | Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2012-07-19 | — | — | US | disclosed |
| US-20120093725-A1 | Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2012-04-19 | — | — | US | disclosed |
| EP-2416806-A1 | FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116209-A1 | FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-10-14 | — | — | WO | disclosed |
| US-4929380-A | Process for the preparation of a storage-stable liquid detergent composition | HENKEL KOMMANDITGESELLSCHAFT AUG AKTIEN (DE) | 1990-05-29 | — | — | US | disclosed |
| US-4820436-A | Detergents for low laundering temperatures | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-04-11 | — | — | US | disclosed |
| US-4774014-A | Detergent supply pack and process for production | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1988-09-27 | — | — | US | disclosed |
| US-4569838-A | GELLING AGENT OF IOTA-CARRAGEENAN AND XANTHAN GUM MIXTURE WITH PHOSPHONATE ANTINUCLEATING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 1986-02-11 | — | — | US | disclosed |