Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | BLM | P54132 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TYMS | P04818 | 1/20 | 0.65 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL5157252 | 0.97 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL4154009 | 0.97 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL15053407 | 0.97 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL11090194 | 0.97 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL10933099 | 0.94 | LMNA (0.78) | LMNABLMCYP3A4NFKB1PMP22 | |
| Putrescine SCHEMBL16241736 | 0.91 | LMNA (0.83) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL8630078 | 0.91 | LMNA (0.83) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL745120 | 0.91 | — | — | |
| SCHEMBL4526841 | 0.88 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4517389 | 0.88 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9235 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049537-A1 | SCALE TREATMENT IN A HETEROGENEOUS RESERVOIR USING A NON-NEWTONIAN FLUID | SAUDI ARABIAN OIL CO (SA) | 2026-02-19 | — | — | US | claimed |
| US-12529009-B2 | Concentrated flowable washing agent preparation having improved properties | HENKEL AG & CO. KGAA (DE) | 2026-01-20 | — | — | US | claimed |
| US-20260015271-A1 | METHOD FOR IMPROVING CALCIUM CARBONATE SCALE INHIBITOR EFFICIENCY | SAUDI ARABIAN OIL CO (SA) | 2026-01-15 | — | — | US | claimed |
| US-20260009493-A1 | VENTURI-BASED FLOW SYSTEM FOR SCALE INHIBITION | SAUDI ARABIAN OIL CO (SA) | 2026-01-08 | — | — | US | claimed |
| CN-119746314-A | Fire blanket | 比亚迪股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| US-20250109036-A1 | POSITIVE ELECTRODE ACTIVE MATERIAL PRECURSOR, POSITIVE ELECTRODE ACTIVE MATERIAL, PREPARATION METHOD, AND SECONDARY BATTERY | CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) | 2025-04-03 | — | — | US | claimed |
| US-12264299-B2 | Detergent composition | SYMRISE AG (DE) | 2025-04-01 | — | — | US | claimed |
| CN-119708951-A | Scale inhibition coating and scale inhibition coating | 佛山市法恩洁具有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119528315-A | Stable reducing iron-sulfur-based slurry and preparation method and application thereof | 南京师范大学 | 2025-02-28 | — | — | CN | claimed |
| CN-116410732-B | Proppant with anti-scale corrosion inhibition performance and preparation method thereof | 中国石油天然气股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| US-4259200-A | METAL COMPLEX OF ETHYLENEDIAMINE TETRAMETHYLENEPHOSPHONIC ACID AS STABILIZER | LEVER BROTHERS COMPANY (US) | 1981-03-31 | — | — | US | claimed |
| EP-0015887-A1 | Improved laundering method | THE PROCTER & GAMBLE COMPANY (US) | 1980-09-17 | — | — | EP | claimed |
| US-4220562-A | Laundry additive product | THE PROCTER & GAMBLE COMPANY (US) | 1980-09-02 | — | — | US | claimed |
| US-4209398-A | ANTISCALING AND ANTIDEPOSIT AGENTS; ACRYLIC POLYMERS, PHOSPHORUS COMPOUNDS, METAL SALTS | KURITA WATER INDUSTRIES LTD. (JP) | 1980-06-24 | — | — | US | claimed |
| US-4183915-A | Stable solution for dental remineralization | COLGATE-PALMOLIVE COMPANY (US) | 1980-01-15 | — | — | US | claimed |
| EP-0006268-A1 | Washing and softening compositions and processes for making them | THE PROCTER & GAMBLE COMPANY (US) | 1980-01-09 | — | — | EP | claimed |
| US-4177258-A | Dentifrice for dental remineralization | COLGATE PALMOLIVE COMPANY (US) | 1979-12-04 | — | — | US | claimed |
| EP-0000226-A1 | Laundry additive substrate for stain removal | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-10 | — | — | EP | claimed |
| US-4111855-A | ANIONIC AND NONIONIC SURFACTANT, POLYACID, CALCIUM IONS, PROTEOLYTIC ENZYME, WATER, ALCOHOL | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4110262-A | ETHOXYLATED NONIONIC SURFACTANT, POLYACID, CARRIER | THE PROCTER & GAMBLE COMPANY (US) | 1978-08-29 | — | — | US | claimed |