Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TYMS | P04818 | 1/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL4154009 | 1.00 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL69119 | 0.97 | LMNA (0.78) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL15053407 | 0.94 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| Ethylenediamine SCHEMBL11090194 | 0.94 | LMNA (0.74) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4530130 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4532973 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4524881 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL768276 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4517389 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL767253 | 0.92 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645438-A | Multifunctional plastic curing petroleum drilling plugging material and preparation and application thereof | 深圳市迈威石油设备技术有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-114873966-B | Hole-sealing solidifying expansion material for mine | 应急管理部信息研究院 | 2023-02-24 | — | — | CN | claimed |
| CN-114873966-A | Mining hole sealing curing expansion material | 应急管理部信息研究院 | 2022-08-09 | — | — | CN | claimed |
| US-6960655-B2 | Disposable product containing cationic chitosan material, together with an odor absorbent agent and/or a chelating agent provides synergistic odor control towards bodily fluids like menses | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-01 | — | — | US | claimed |
| CN-117645438-A | Multifunctional plastic curing petroleum drilling plugging material and preparation and application thereof | 深圳市迈威石油设备技术有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-114873966-B | Hole-sealing solidifying expansion material for mine | 应急管理部信息研究院 | 2023-02-24 | — | — | CN | disclosed |
| CN-113773822-B | Steam flooding profile control agent and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-113773821-B | High-temperature blockage-regulating cleanup additive and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-114873966-A | Mining hole sealing curing expansion material | 应急管理部信息研究院 | 2022-08-09 | — | — | CN | disclosed |
| CN-113773821-A | High-temperature blockage-regulating cleanup additive and preparation method and application thereof | 中国石油天然气股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113773822-A | Steam flooding profile control agent and preparation method and application thereof | 中国石油天然气股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-106811184-B | Composite inorganic plugging agent for oil well water plugging and preparation method thereof | 中国石油天然气股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| US-6713442-B2 | MIXTURE CONTAINING ANIONIC AND NONIONIC SURFACTANTS | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. | 2004-03-30 | — | — | US | disclosed |
| WO-2003064582-A1 | DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003064583-A1 | DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2003-08-07 | — | — | WO | disclosed |
| US-20030144161-A1 | Detergent compositions | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. | 2003-07-31 | — | — | US | disclosed |
| WO-2003053487-A1 | ABSORBENT ARTICLE | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | WO | disclosed |
| WO-2002094329-A1 | ODOR CONTROL CONTAINING ABSORBENT MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-28 | — | — | WO | disclosed |
| EP-1163321-A1 | ANTIMICROBIAL ACID CLEANER FOR USE ON ORGANIC SOIL | ECOLAB INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056853-A1 | ANTIMICROBIAL ACID CLEANER FOR USE ON ORGANIC SOIL | ECOLAB INC. (US) | 2000-09-28 | — | — | WO | disclosed |