Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349851 | 0.87 | CA12 (0.54) | CA12CA4CA7CA9CA14 | |
| SCHEMBL6254 | 0.87 | CA12 (0.54) | CA12CA4CA7CA9CA14 | |
| SCHEMBL3384278 | 0.85 | CA12 (0.53) | CA12CA4CA7CA9CA14 | |
| SCHEMBL3384286 | 0.85 | CA12 (0.53) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL14833086 | 0.85 | TSHR (0.55) | CA12CA4CA7CA9CA14 | |
| Water SCHEMBL29222618 | 0.84 | CA12 (0.51) | CA12CA4CA7CA9CA14 | |
| Water SCHEMBL30987561 | 0.84 | CA12 (0.51) | CA12CA4CA7CA9CA14 | |
| SCHEMBL26669966 | 0.80 | CA12 (0.42) | CA12CA4CA7CA9CA14 | |
| Isothiocyanate SCHEMBL8518639 | 0.80 | CA12 (0.47) | CA12CA4CA7CA9CA14 | |
| SCHEMBL3009308 | 0.76 | CASP6 (0.59) | CA12CA4CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122627-B2 | Lactam inhibitors of Hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-17 | — | — | US | disclosed |
| US-20040171556-A1 | Methods for inhibiting proteasome | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-02 | — | — | US | disclosed |
| WO-2004064755-A2 | METHODS FOR INHIBITING PROTEASOME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20030008828-A1 | Diagnostic kits; for therapy of viral infection; as assat standard or reagent | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008828-A1 | Diagnostic kits; for therapy of viral infection; as assat standard or reagent | PRSS3, PRSS1, PREP | CA12 381/4885CA4 1495/4885CA7 596/4885 |
| US-20040171556-A1 | Methods for inhibiting proteasome | PSMB1, PSMB11, PSMG3 | CA12 4336/4885CA4 4367/4885CA7 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.