Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.61 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.61 |
| ▸ | FABP3 | P05413 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663261 | 0.87 | FABP4 (0.74) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5839103 | 0.87 | FABP4 (0.61) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5838836 | 0.84 | FABP4 (0.61) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5838308 | 0.83 | FABP4 (0.63) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5663405 | 0.81 | FABP4 (0.88) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5839914 | 0.81 | FABP4 (0.88) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL2453382 | 0.81 | LMNA (0.62) | TP53MRGPRX4MEN1NPC1MITF | |
| SCHEMBL5840313 | 0.81 | FABP4 (0.65) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5840237 | 0.80 | FABP4 (0.58) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5839028 | 0.80 | FABP4 (0.55) | FABP4FABP5FABP3TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |