Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950218 | 0.83 | LMNA (0.73) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL353141 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL30792459 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL29412848 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL17180592 | 0.81 | LMNA (0.70) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL105459 | 0.81 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL29799007 | 0.81 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2683707 | 0.79 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL5250407 | 0.79 | SMN1; SMN2 (0.96) | LMNASMN1; SMN2POLBNPC1L3MBTL1 | |
| SCHEMBL38770 | 0.79 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2POLBNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
| US-6469003-B1 | COMPOUNDS HAVING CELL ADHESION INHIBITING ACTIVITY | NIHON NOHYAKU CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1130015-A1 | PYRIDAZINONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2001-09-05 | — | — | EP | disclosed |