SCHEMBL58398

SCHEMBL58398

CCCc1ccc(P(=O)(C(=O)c2c(C)ccc3ccccc23)C(=O)c2c(C)ccc3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
ALOX15 P16050 1/20 0.38
TRPV1 Q8NER1 1/20 0.37
CNR2 P34972 6/20 0.36
NCEH1 Q6PIU2 2/20 0.36
CNR1 P21554 4/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
PLK1 P53350 1/20 0.35
CYP1A2 P05177 3/20 0.34
TSHR P16473 2/20 0.34
CYP2C19 P33261 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2771807 0.84 TAS1R3 (0.46) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL2770469 0.82 TAS1R3 (0.42) PDE10ATAS1R3TAS1R1TAS1R2KMT2A
SCHEMBL57936 0.81 IDO1 (0.50) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL29375600 0.80 TAS1R3 (0.43) TAS1R3TAS1R1TAS1R2ALOX15CNR2
SCHEMBL58820 0.80 TAS1R3 (0.43) TAS1R3TAS1R1TAS1R2ALOX15CNR2
SCHEMBL2772458 0.80 ABCG2 (0.48) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL29934000 0.76 TSHR (0.38) PDE10ATRPV1CNR2NCEH1KMT2A
SCHEMBL23535273 0.75 PDE10A (0.41) PDE10ATAS1R3TAS1R1TAS1R2ALOX15
SCHEMBL23535272 0.75 PDE10A (0.41) PDE10ATAS1R3TAS1R1TAS1R2ALOX15
SCHEMBL28674909 0.74 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2POLBPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4286163-B1 ELECTRON BEAM CURABLE INK, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2026-04-01 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4681930-A1 IMAGE RECORDING METHOD, METHOD FOR MANUFACTURING LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-20250375971-A1 IMAGE RECORDING METHOD, MANUFACTURING METHOD OF LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM CORP (JP) 2025-12-11 US disclosed
EP-4660262-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK, ACTIVE ENERGY RAY-CURABLE INK SET, AND IMAGE RECORDING METHOD FUJIFILM Corporation (JP) 2025-12-10 EP disclosed
US-20250340747-A1 ACTIVE ENERGY RAY CURABLE TYPE INK JET INK, ACTIVE ENERGY RAY CURABLE TYPE INK SET, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2025-11-06 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
US-20050221210-A1 Electrophotographic photoconductor and image formation method, image formation apparatus, and process cartridge for image formation apparatus using the electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2005-10-06 US disclosed
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
WO-2003010124-A1 POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed
EP-0825201-B1 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2002-02-27 EP disclosed
EP-1044777-A1 Molding method for corrosion-resistant FRP SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-10-18 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A PDE10A 2313/4885TAS1R3 379/4885TAS1R1 292/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 PDE10A 1458/4885TAS1R3 182/4885TAS1R1 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.