SCHEMBL2771807

SCHEMBL2771807

Cc1ccc2ccccc2c1C(=O)P(=O)(C(=O)c1c(C)ccc2ccccc12)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
CYP1A2 P05177 2/20 0.42
TSHR P16473 2/20 0.42
CYP2A6 P11509 2/20 0.42
HPGD P15428 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HCRTR1 O43613 4/20 0.38
HCRTR2 O43614 4/20 0.38
WDR5 P61964 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2770469 0.91 TAS1R3 (0.42) TAS1R3TAS1R1TAS1R2CYP1A2TSHR
SCHEMBL29375600 0.87 TAS1R3 (0.43) TAS1R3TAS1R1TAS1R2CYP1A2TSHR
SCHEMBL58820 0.87 TAS1R3 (0.43) TAS1R3TAS1R1TAS1R2CYP1A2TSHR
SCHEMBL2772458 0.86 ABCG2 (0.48) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL58398 0.84 PDE10A (0.41) TAS1R3TAS1R1TAS1R2CYP1A2TSHR
SCHEMBL28674909 0.83 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2CYP1A2TSHR
SCHEMBL57936 0.83 IDO1 (0.50) TAS1R3TAS1R1TAS1R2ALDH1A1MEN1
SCHEMBL29657949 0.80 CA2 (0.38) CYP1A2TSHRMEN1KMT2ANPC1
SCHEMBL599633 0.80 CA2 (0.38) CYP1A2TSHRMEN1KMT2ANPC1
SCHEMBL246249 0.80 L3MBTL1 (0.41) HPGDALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
EP-4329704-B1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-08 EP disclosed
EP-3880156-B1 STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-08-20 EP disclosed
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
EP-4580818-A1 ONE COMPONENT, UV-CURED PRIMER MATERIAL FOR REPAIRING SURFACE IMPERFECTIONS Illinois Tool Works Inc. (US) 2025-07-09 EP disclosed
EP-4558086-A1 CURABLE COMPOSITION FOR PRODUCING TRANSPARENT ORTHODONTIC ATTACHMENTS Solventum Intellectual Properties Company (US) 2025-05-28 EP disclosed
US-20140329205-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2014-11-06 US disclosed
EP-2785307-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2014-10-08 EP disclosed
WO-2013082337-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-06 WO disclosed
US-7723445-B2 Curable resin composition, molded product, and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2010-05-25 US disclosed
US-20090008834-A1 Curable resin composition, molded product, and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-01-08 US disclosed
EP-1785440-A1 CURABLE RESIN COMPOSITION, SHAPED ARTICLE AND METHOD FOR PRODUCING SAME Showa Highpolymer Co., Ltd. (JP) 2007-05-16 EP disclosed
US-20020022130-A1 UV-curable binder composition for magnetic recording media and photoinitiator mixture EMTEC MAGNETICS GMBH (DE) 2002-02-21 US disclosed
US-4868091-A USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING BASF AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329205-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF ESD, CAD, GSS TAS1R3 97/4885TAS1R1 65/4885TAS1R2 111/4885
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A TAS1R3 379/4885TAS1R1 292/4885TAS1R2 273/4885
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC TAS1R3 305/4885TAS1R1 227/4885TAS1R2 334/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 TAS1R3 182/4885TAS1R1 73/4885TAS1R2 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.