SCHEMBL5840669

SCHEMBL5840669

O=c1nc(-c2ccc(-c3ccccc3)cc2)c2c(=O)nc(-c3ccc(-c4ccccc4)cc3)c1=2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.45
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
GLA P06280 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A2 P05177 1/20 0.42
PKM P14618 1/20 0.42
XDH P47989 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL771038 0.95 KDM4E (0.46) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL7556164 0.90 KDM4E (0.60) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL9351559 0.90 KDM4E (0.60) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL8502939 0.88 MEN1 (0.47) XDHMEN1KMT2AADORA1
SCHEMBL8125107 0.88 TDP1 (0.58) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL9833132 0.88 TDP1 (0.58) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL9070411 0.84 XDH (0.41) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL5892108 0.82 ALDH1A1 (0.41) KDM4ELMNAGAAL3MBTL1ALDH1A1
SCHEMBL9833339 0.82 TSHR (0.48) LMNASMN1; SMN2TDP1TSHRPOLB
SCHEMBL10607584 0.81 ADORA1 (0.55) KDM4ELMNASMN1; SMN2CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737723-B1 Pigment compositions based on 3,6-di(4-biphenyl)-1,4-diketopyrrolo (3,4 c)-pyrrole CIBA SC HOLDING AG (CH) 1999-12-29 EP claimed
US-5869625-A PAINTS CIBA SPECIALTY CHEMICAL CORPORATION (US) 1999-02-09 US claimed
US-5827364-A Pigment compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-10-27 US claimed
US-5565578-A PURIFYING THE CHROME RED BY SALT FORMATION WITH A BASE DISSOLVING IN DIMETHYLSULFOXIDE, DESALTING IN ALKANOL CIBA-GEIGY CORPORATION (US) 1996-10-15 US claimed
JP-8295816-A None JP disclosed
EP-3199602-B1 INK COMPOSITION SET SEIKO EPSON CORP (JP) 2019-10-09 EP disclosed
US-10400124-B2 Ink composition set SEIKO EPSON CORPORATION (JP) 2019-09-03 US disclosed
US-9878537-B2 Image forming method SEIKO EPSON CORPORATION (JP) 2018-01-30 US disclosed
US-20170282557-A1 IMAGE FORMING METHOD SEIKO EPSON CORPORATION (JP) 2017-10-05 US disclosed
US-20170218216-A1 INK COMPOSITION SET SEIKO EPSON CORPORATION (JP) 2017-08-03 US disclosed
EP-3199602-A1 INK COMPOSITION SET Seiko Epson Corporation (JP) 2017-08-02 EP disclosed
EP-2723805-B1 COLORED POLYIMIDE FILMS AND METHODS RELATING THERETO DU PONT (US) 2017-07-26 EP disclosed
EP-0672729-A1 Diketopyrrolopyrrol pigment with a high hue purity CIBA-GEIGY AG (CH) 1995-09-20 EP disclosed
EP-0232222-B1 Process for the preparation of brominated pyrrolo-[3,4-c]-pyrroles CIBA-GEIGY AG (CH) 1992-09-09 EP disclosed
US-5106406-A Method for desalination and rehabilitation of irrigated soil SOTAC CORPORATION (US) 1992-04-21 US disclosed
US-4923500-A Method for desalination and rehabilitation of irrigated soil SOTAC CORPORATION 1990-05-08 US disclosed
EP-0323506-A4 METHOD FOR DESALINATION AND REHABILITATION OF IRRIGATED SOIL. SYLLING TRUMAN V (US) 1990-01-08 EP disclosed
EP-0323506-A1 METHOD FOR DESALINATION AND REHABILITATION OF IRRIGATED SOIL SOTAC CORPORATION (US) 1989-07-12 EP disclosed
US-4810802-A RED PIGMENTS FOR POLYVINYL CHLORIDE CIBA-GEIGY CORPORATION (US) 1989-03-07 US disclosed
WO-1989000155-A1 METHOD FOR DESALINATION AND REHABILITATION OF IRRIGATED SOIL SYLLING TRUMAN V (US) 1989-01-12 WO disclosed