SCHEMBL771038

SCHEMBL771038

O=c1nc(-c2ccccc2)c2c(=O)nc(-c3ccccc3)c1=2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
HPGD P15428 3/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GLA P06280 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PKM P14618 1/20 0.45
XDH P47989 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALOX15 P16050 1/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840669 0.95 KDM4E (0.45) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL7556164 0.89 KDM4E (0.60) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL9351559 0.89 KDM4E (0.60) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL9833132 0.88 TDP1 (0.58) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL8502939 0.88 MEN1 (0.47) XDHMEN1KMT2A
SCHEMBL8125107 0.88 TDP1 (0.58) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL9070411 0.88 XDH (0.41) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL10607584 0.84 ADORA1 (0.55) KDM4ELMNASMN1; SMN2NPC1RAB9A
SCHEMBL5892108 0.82 ALDH1A1 (0.41) KDM4EHPGDLMNAALDH1A1GLA
SCHEMBL9833339 0.82 TSHR (0.48) LMNASMN1; SMN2TSHRTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412431-B1 PIGMENT COMPOSITIONS AND PIGMENTED WATER-BASED COATING MATERIALS BASF SE (DE) 2014-05-14 EP claimed
US-7081540-B2 Pigment compositions and pigmented water-based coating materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-07-25 US claimed
EP-0874025-B1 Beta quinacridone pigment CIBA SC HOLDING AG (CH) 2005-06-08 EP claimed
US-20040194666-A1 Pigment compositions for coatings CIBA SPECIALTY CHEMICALS CORP. 2004-10-07 US claimed
US-20040116559-A1 Pigment compositions and pigmented water-based coating materials CIBA SPECIALTY CHEMICAL CORP. 2004-06-17 US claimed
EP-1412431-A1 PIGMENT COMPOSITIONS AND PIGMENTED WATER-BASED COATING MATERIALS Ciba SC Holding AG (CH) 2004-04-28 EP claimed
WO-2002085987-A1 PIGMENT COMPOSITIONS AND PIGMENTED WATER-BASED COATING MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-31 WO claimed
US-6248165-B1 ORGANIC RED PIGMENTS FOR CELLULOSES AND PLASTICS; INCORPORATING A THIRD COMPONENT OF A DIKETOPYRROLE OR QUINACRIDONE PIGMENT INTO THE CRYSTAL LATTICE OF THE MIXED CRYSTAL; COLORFASTNESS; WEATHERPROOFING CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-19 US claimed
US-6090196-A LIQUID PHASE OXIDATION OF 6,13-DIHYDROQUINACRIDONE WITH M-NITROBENZENE SULFONIC ACID SALT IN PRESENCE OF A BASE AND QUINACRIDONE MONOSULFONIC ACID GRAIN GROWTH INHIBITOR CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-07-18 US claimed
EP-0696620-B1 Solid solutions of pyrrolo- 3,4-c -pyrroles with quinacridonequinones CIBA SC HOLDING AG (CH) 2000-04-26 EP claimed
US-5472496-A Ternery component; light and weatherfastness; useful as colorant in plastics, inks and automotive paints CIBA-GEIGY CORPORATION (US) 1995-12-05 US claimed
US-RE35009-E Diketopyrrolopyrrole pigments in platelet form CIBA-GEIGY CORPORATION (US) 1995-08-01 US claimed
WO-1994029319-A1 14-SUBSTITUTED MARCFORTINES AND DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS THE UPJOHN COMPANY (US) 1994-12-22 WO claimed
EP-0408498-B1 Plate like organic effect pigments CIBA GEIGY AG (CH) 1994-09-14 EP claimed
US-5347014-A In a platelet form; recrstallization from aromatic solvents; coloring materials for casting and molding, pigmenting lacquers, enamels; automotive paints CIBA-GEIGY CORPORATION (US) 1994-09-13 US claimed
EP-0604370-A1 Process for preparing a platelet form of 1,4-diketo-3,6-diphenylpyrrolo-(3,4,c)-pyrrole CIBA-GEIGY AG (CH) 1994-06-29 EP claimed
EP-0232222-B1 Process for the preparation of brominated pyrrolo-[3,4-c]-pyrroles CIBA-GEIGY AG (CH) 1992-09-09 EP claimed
US-5095122-A DIKETOPYRROLOPYRROLE PIGMENTS IN PLATELET FORM CIBA-GEIGY CORPORATION (US) 1992-03-10 US claimed
EP-0430875-A2 Water-based coating materials containing specific modified organic pigments CIBA-GEIGY AG (CH) 1991-06-05 EP claimed
EP-0408498-A2 Plate like organic effect pigments CIBA-GEIGY AG (CH) 1991-01-16 EP claimed