Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091957 | 0.93 | LMNA (0.43) | TSHRSMN1; SMN2POLBCYP2D6TDP1 | |
| SCHEMBL5840669 | 0.82 | KDM4E (0.45) | TSHRSMN1; SMN2POLBTDP1LMNA | |
| SCHEMBL771038 | 0.82 | KDM4E (0.46) | TSHRSMN1; SMN2POLBTDP1LMNA | |
| SCHEMBL9835102 | 0.78 | TDP1 (0.43) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL34718 | 0.78 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL30029777 | 0.78 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL21993467 | 0.78 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL15849846 | 0.78 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL7556164 | 0.77 | KDM4E (0.60) | SMN1; SMN2CYP2D6LMNA | |
| SCHEMBL9351559 | 0.77 | KDM4E (0.60) | SMN1; SMN2CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224445-B1 | PYRROLO-PYRROLE PIGMENT PREPARATIONS, THEIR PREPARATION PROCESS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |