Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.89 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.89 |
| ▸ | HPGD | P15428 | 2/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.89 |
| ▸ | AR | P10275 | 1/20 | 0.89 |
| ▸ | TSHR | P16473 | 1/20 | 0.89 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.89 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.89 |
| ▸ | HTR6 | P50406 | 1/20 | 0.89 |
| ▸ | ESRRG | P62508 | 1/20 | 0.89 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TYR | P14679 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisphenol A SCHEMBL8051951 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL31267162 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL8058731 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL15868669 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL27996 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL15062 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL9774987 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL278218 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL3170263 | 0.94 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL10624830 | 0.92 | ESR1 (0.94) | ESR1ESR2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159693-A1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | KANEKA AEROSPACE LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20210102035-A1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | KANEKA AEROSPACE LLC (US) | 2021-04-08 | — | — | US | disclosed |
| US-8748563-B2 | Curable compositions | HENKEL AG & CO. KGAA (DE) | 2014-06-10 | — | — | US | disclosed |
| EP-2217651-B1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | HENKEL AG & CO KGAA (DE) | 2013-08-28 | — | — | EP | disclosed |
| US-20120329945-A1 | BENZOXAZINE-CONTAINING COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120301662-A1 | CURABLE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2012-11-29 | — | — | US | disclosed |
| EP-2493958-A1 | BENZOXAZINE-CONTAINING COMPOSITIONS | Henkel AG & Co. KGaA (DE) | 2012-09-05 | — | — | EP | disclosed |
| EP-2331624-B1 | BENZOXAZINE-BASED COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | HENKEL AG & CO KGAA (DE) | 2012-02-15 | — | — | EP | disclosed |
| US-20110172356-A1 | BENZOXAZINE-BASED COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | KREILING STEFAN | 2011-07-14 | — | — | US | disclosed |
| EP-2336221-A1 | Curable compositions | Henkel AG & Co. KGaA (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-2324077-A1 | EPOXY-BASED COMPOSITION CONTAINING COPOLYMER | Henkel AG & Co. KGaA (DE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2011050834-A1 | BENZOXAZINE-CONTAINING COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011047939-A1 | CURABLE COMPOSITION COMPRISING A BENZOXAZINE COMPOUND AND A SULFONIC ACID ESTER HAVING A CYCLIC STRUCTURE AS A HEAT-ACTIVATABLE CATALYST | HENKEL AG & CO. KGAA (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2217651-A2 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | Henkel AG & Co. KGaA (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20100204400-A1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| WO-2010031826-A1 | BENZOXAZINE-BASED COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | HENKEL AG & CO. KGAA (DE) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010029096-A1 | EPOXY-BASED COMPOSITION CONTAINING COPOLYMER | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | WO | disclosed |
| WO-2009133011-A1 | BENZOXAZINE COMPOSITIONS CONTAINING (CO)POLYMER | HENKEL AG & CO. KGAA (DE) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009075743-A2 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS | HENKEL AG & CO. KGAA (DE) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009071991-A2 | NANOPARTICLE SILICA FILLED BENZOXAZINE COMPOSITIONS | HENKEL AG & CO. KGAA (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329945-A1 | BENZOXAZINE-CONTAINING COMPOSITIONS | XDH, TYR, CYP4Z1 | ESR1 705/4885ESR2 1642/4885CYP3A4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.