Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512737 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL4027568 | 0.80 | TDP1 (0.47) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL15491314 | 0.80 | POLB (0.41) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL8205763 | 0.78 | GPR3 (0.54) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL5049954 | 0.77 | POLB (0.42) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL15491313 | 0.76 | POLB (0.60) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL9364466 | 0.76 | ERN1 (0.51) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL1128076 | 0.73 | MAPT (0.62) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL29948882 | 0.73 | MAPT (0.62) | KDM4EALDH1A1HPGDGLATDP1 | |
| SCHEMBL28219986 | 0.73 | MAOA (0.64) | KDM4EALDH1A1HPGDGLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925289-A | Preparation method of 5-bromo-2-chlorobenzoic acid | 浙江美诺华药物化学有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-115443436-A | Laminated film for pattern formation, non-photosensitive screen printing plate, and method for producing same | 株式会社村上 | 2022-12-06 | — | — | CN | disclosed |
| EP-1553449-B1 | ACTIVE ENERGY RAY SENSITIVE RESIN COMPOSITION, ACTIVE ENERGY RAY SENSITIVE RESIN FILM AND METHOD FOR FORMING PATTERN USING SAID FILM | MURAKAMI CO LTD (JP) | 2016-01-20 | — | — | EP | disclosed |
| CN-102766091-A | Preparation method of 3-(3-quinolyl)-2-propyne-1-alcohol | SHANGHAI INST PHARM INDUSTRY | 2012-11-07 | — | — | CN | disclosed |
| US-7009055-B2 | such as (methyl-sulfonyl)methyl bromo-quinoline by treatment of dibromomethyl bromo-quinoline with sodium methanesulfinate in solvent; chemical intermediates in production of phosphodiesterase inhibitors | MERCK & CO., INC. (US) | 2006-03-07 | — | — | US | disclosed |
| US-20050227166-A1 | Active energy ray sensitive resin composition, active energy ray sensitive resin film and method for forming pattern using said film | MURAKAMI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-1553449-A1 | ACTIVE ENERGY RAY SENSITIVE RESIN COMPOSITION, ACTIVE ENERGY RAY SENSITIVE RESIN FILM AND METHOD FOR FORMING PATTERN USING SAID FILM | Murakami Co., Ltd. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-20040176604-A1 | Preparation of sulfonyl quinoline | XU FENG (US) | 2004-09-09 | — | — | US | disclosed |
| WO-2003010137-A1 | PREPARATION OF SULFONYL QUINOLINE | MERCK & CO., INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| US-5145760-A | POSITIVE-WORKING PHOTOSENSITIVE ELECTROSTATIC MASTER WITH IMPROVED INVIRONMENTAL LATITUDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176604-A1 | Preparation of sulfonyl quinoline | STS, SULT2A1, BRD7 | KDM4E 1298/4885ALDH1A1 2511/4885HPGD 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.