SCHEMBL5841335

SCHEMBL5841335

CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@@H]2COC(c3ccccc3)O[C@H]2[C@@H]1OCc1ccccc1

nearest known ligand 0.89

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.89
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ SELP P16109 1/20 0.43
▸ ALDH1A1 P00352 3/20 0.42
▸ PKM P14618 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ LMNA P02545 2/20 0.38
▸ MAG P20916 1/20 0.37
▸ HRAS P01112 1/20 0.36
▸ TP53 P04637 2/20 0.36
▸ MDM2 Q00987 2/20 0.36
▸ BCHE P06276 1/20 0.36
▸ KLK7 P49862 1/20 0.35
▸ KLK5 Q9Y337 1/20 0.35
▸ MDM4 O15151 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ HSP90AB1 P08238 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841072 1.00 L3MBTL1 (0.89) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL11642846 0.94 L3MBTL1 (1.00) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL8720751 0.94 L3MBTL1 (0.85) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL11469354 0.94 L3MBTL1 (0.85) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL24352060 0.93 L3MBTL1 (0.82) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL7566017 0.93 L3MBTL1 (0.82) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL7888493 0.93 L3MBTL1 (0.82) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL7887139 0.92 L3MBTL1 (0.79) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL7570170 0.90 L3MBTL1 (0.77) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL6810084 0.90 L3MBTL1 (0.77) L3MBTL1KMT2AMEN1SELPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098195-B2 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells HEALTH RESEARCH, INC. (US) 2006-08-29 — — US disclosed
US-20040058888-A1 Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides ALCHEMIA PTY LTD. (AU) 2004-03-25 — — US disclosed
US-20030148997-A1 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-08-07 — — US disclosed
EP-1257558-A1 METHODS FOR SYNTHESIS OF ALPHA-D-GAL (1- 3) GAL-CONTAINING OLIGOSACCHARIDES Alchemia Pty Ltd (AU) 2002-11-20 — — EP disclosed
WO-2001051499-A1 METHODS FOR SYNTHESIS OF α-D-GAL (1→3) GAL-CONTAINING OLIGOSACCHARIDES ALCHEMIA PTY LTD (AU) 2001-07-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030148997-A1 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells FUT5, FUT6, OGT L3MBTL1 3765/4885KMT2A 3787/4885MEN1 4766/4885
US-20040058888-A1 Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides B4GALT1, B3GAT3, FUT5 L3MBTL1 204/4885KMT2A 638/4885MEN1 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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