Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156121 | 0.85 | NPSR1 (0.39) | ENPP2ALDH1A1SMN1; SMN2MAPTCYP26B1 | |
| SCHEMBL6610175 | 0.81 | ACHE (0.50) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL2475622 | 0.80 | ORAI1 (0.48) | LMNAENPP2ALDH1A1RECQLCYP26B1 | |
| SCHEMBL6379719 | 0.80 | ENPP2 (0.48) | LMNAENPP2ALDH1A1DRD2DRD4 | |
| SCHEMBL29133596 | 0.79 | CA2 (0.46) | ACHELMNAENPP2DRD2DRD4 | |
| SCHEMBL2474216 | 0.79 | ACHE (0.43) | ACHELMNAENPP2DRD2DRD4 | |
| SCHEMBL29435910 | 0.79 | ACHE (0.56) | ACHELMNAENPP2ALDH1A1GAA | |
| SCHEMBL557190 | 0.79 | ACHE (0.56) | ACHELMNAENPP2ALDH1A1GAA | |
| SCHEMBL29125537 | 0.79 | MAOB (0.53) | LMNAENPP2ALDH1A1GAAMEN1 | |
| Anthracene SCHEMBL5574730 | 0.77 | CA1 (0.42) | ENPP2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115959993-B | Synthesis method of 2-aryl propionic acid compound | 山东中医药大学 | 2025-01-07 | — | — | CN | claimed |
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | claimed |
| CN-114262330-B | Fascaplysin derivative, preparation method and application thereof in resisting MRSA | 宁波大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-111303150-B | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | disclosed |
| US-7138530-B2 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-7109354-B2 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | SUBASINGHE NALIN | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | ACHE 1244/4885LMNA 4410/4885ENPP2 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.