Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475622 | 0.91 | ORAI1 (0.48) | CA1CA2ORAI1ORAI2ORAI3 | |
| SCHEMBL28424021 | 0.84 | CA1 (0.48) | CA1CA2ORAI1ORAI2ORAI3 | |
| Benzofuran SCHEMBL29036402 | 0.79 | CA2 (0.35) | CA1CA2ORAI1ORAI2ORAI3 | |
| Monoethanolamine SCHEMBL9783347 | 0.79 | ALDH1A1 (0.40) | CA1CA2ORAI1ORAI2ORAI3 | |
| SCHEMBL29361893 | 0.79 | ALDH1A1 (0.41) | CA1CA2CYP1A2KDM4EMEN1 | |
| SCHEMBL5134895 | 0.79 | ALDH1A1 (0.41) | CA1CA2CYP1A2KDM4EMEN1 | |
| SCHEMBL6379719 | 0.79 | ENPP2 (0.48) | CA1CA2ORAI1ORAI2ORAI3 | |
| SCHEMBL5317235 | 0.78 | ORAI1 (0.41) | CA1CA2ORAI1ORAI2ORAI3 | |
| SCHEMBL12538977 | 0.78 | CA1 (0.39) | CA1CA2ORAI1ORAI2ORAI3 | |
| SCHEMBL29133596 | 0.78 | CA2 (0.46) | CA1CA2ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070827-A2 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | TNNI3, TNNT2, TNNC1 | CA1 1664/4885CA2 517/4885ORAI1 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.