Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | CRHBP | P24387 | 2/20 | 0.71 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.58 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047751 | 0.94 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL14165160 | 0.92 | MAPT (0.60) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL21474173 | 0.92 | MAPT (0.60) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL17746790 | 0.90 | SMN1; SMN2 (0.69) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL12048280 | 0.90 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL17746789 | 0.90 | SMN1; SMN2 (0.69) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL12047857 | 0.88 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL12048225 | 0.88 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL12048353 | 0.88 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP | |
| SCHEMBL12048633 | 0.86 | KMT2A (0.69) | ALDH1A1MEN1KMT2AL3MBTL1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294713-A | A kind of preparation method of imidazoles methylamine like derivative | 西华大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-110294714-A | Imidazoles methylamine like derivative and its synthetic method with indoles amine -2,3- dioxygenase (IDO) inhibitor activity | 西华大学 | 2019-10-01 | — | — | CN | disclosed |
| EP-3147333-B1 | DISPERSE DYE COMPOSITION, DISPERSE DYE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG RUNTU CO LTD (CN) | 2017-11-01 | — | — | EP | disclosed |
| US-9028977-B2 | Compound, method for preparing same and organic electronic device using same | LG CHEM, LTD. (KR) | 2015-05-12 | — | — | US | disclosed |
| US-9028977-B2 | Compound, method for preparing same and organic electronic device using same | LG CHEM, LTD. (KR) | 2015-05-12 | — | — | US | disclosed |
| US-8968884-B2 | Compound and organic light emitting device using the same | LG CHEM, LTD. (KR) | 2015-03-03 | — | — | US | disclosed |
| US-8968884-B2 | Compound and organic light emitting device using the same | LG CHEM, LTD. (KR) | 2015-03-03 | — | — | US | disclosed |
| US-8410475-B2 | Compounds and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2013-04-02 | — | — | US | disclosed |
| US-8410475-B2 | Compounds and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2013-04-02 | — | — | US | disclosed |
| US-8071227-B2 | Compounds and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2011-12-06 | — | — | US | disclosed |
| US-20070292715-A1 | New Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-12-20 | — | — | US | disclosed |
| US-20070292715-A1 | New Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-12-20 | — | — | US | disclosed |
| US-20070262706-A1 | New Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-11-15 | — | — | US | disclosed |
| US-20070262706-A1 | New Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-11-15 | — | — | US | disclosed |
| US-20070247059-A1 | Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-10-25 | — | — | US | disclosed |
| US-20070247059-A1 | Compound and Organic Light Emitting Device Using the Same | LG CHEM, LTD. (KR) | 2007-10-25 | — | — | US | disclosed |
| US-7067549-B2 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2006-06-27 | — | — | US | disclosed |
| US-20050192292-A1 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2005-09-01 | — | — | US | disclosed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192292-A1 | Pyrrolidone carboxamides | NPY1R, NPY5R, NPY2R | ALDH1A1 3034/4885MEN1 3619/4885KMT2A 3347/4885 |
| US-20070247059-A1 | Compound and Organic Light Emitting Device Using the Same | PPOX, CRY1, CRY2 | ALDH1A1 318/4885MEN1 2423/4885KMT2A 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.