Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18060991 | 0.86 | LTA4H (0.47) | PTGIRLRRK2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29083009 | 0.85 | CYP1A2 (0.45) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9487582 | 0.85 | CA12 (0.60) | PTGIRLRRK2CA12CA1CA2 | |
| SCHEMBL38663217 | 0.85 | CA12 (0.60) | PTGIRLRRK2CA12CA1CA2 | |
| SCHEMBL8738414 | 0.84 | MAPT (0.58) | PTGIRLRRK2CA12CA1CA2 | |
| SCHEMBL31345518 | 0.84 | MAPT (0.58) | PTGIRLRRK2CA12CA1CA2 | |
| SCHEMBL6512960 | 0.82 | CYP1A2 (0.42) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL14176623 | 0.82 | MAPT (0.51) | L3MBTL1MAPK1ALDH1A1MAPTSMN1; SMN2 | |
| Nitrogen SCHEMBL10783880 | 0.81 | MAPT (0.55) | PTGIRLRRK2CA12CA1CA2 | |
| SCHEMBL6516678 | 0.81 | CYP1A2 (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683218-B2 | Method for producing thioether compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20080108823-A1 | Method For Producing Thioether Compound | MSD K.K. (JP) | 2008-05-08 | — | — | US | disclosed |
| EP-1806337-A1 | METHOD FOR PRODUCING THIOETHER COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108823-A1 | Method For Producing Thioether Compound | TST, MPST, PPIP5K2 | PTGIR 2705/4885LRRK2 66/4885CA12 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.