Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6122979 | 0.93 | ADRB2 (0.39) | ADRB2ADRB1ADRB3DNM1LMNA | |
| SCHEMBL28049516 | 0.91 | DNM1 (0.32) | ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL441733 | 0.90 | — | — | |
| SCHEMBL10353370 | 0.90 | ADRB2 (0.38) | ADRB2ADRB1ADRB3DNM1LMNA | |
| SCHEMBL9137918 | 0.90 | ADRB2 (0.38) | ADRB2ADRB1ADRB3DNM1LMNA | |
| SCHEMBL2962635 | 0.86 | ADRB2 (0.35) | ADRB2ADRB1ADRB3DNM1LMNA | |
| SCHEMBL250770 | 0.85 | DNM1 (0.46) | DNM1LMNATSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL18334320 | 0.84 | TSHR (0.44) | ADRB2ADRB1ADRB3DNM1LMNA | |
| SCHEMBL15160848 | 0.83 | DNM1 (0.45) | DNM1ALDH1A1 | |
| SCHEMBL6377068 | 0.83 | ADRB2 (0.36) | ADRB2ADRB1ADRB3DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097440-A | PAINTS, ADDITION POLYMERS, PLASTICIZERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-06-27 | — | — | US | claimed |
| US-7078471-B2 | Modified silane compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-07-18 | — | — | US | disclosed |
| US-7053162-B2 | Modified silane compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040229994-A1 | Modified silane compounds | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-11-18 | — | — | US | disclosed |
| US-20040087803-A1 | Modified silane compounds | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-05-06 | — | — | US | disclosed |
| US-5962579-A | LATEX BLEND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-4097440-A | PAINTS, ADDITION POLYMERS, PLASTICIZERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087803-A1 | Modified silane compounds | ITGA8, ITGA1, SIK1 | ADRB2 2601/4885ADRB1 2355/4885ADRB3 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.