SCHEMBL5843340

SCHEMBL5843340

CC(C)COc1c[c]c(F)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
KDM1A O60341 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
XDH P47989 1/20 0.34
SCN9A Q15858 9/20 0.33
SCN5A Q14524 3/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
TLR8 Q9NR97 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25182702 0.83 TSHR (0.40) TSHRTDP1L3MBTL1ALDH1A1GAA
SCHEMBL5843254 0.81 MAPT (0.37) TSHRL3MBTL1ALDH1A1LMNAKMT2A
SCHEMBL5844611 0.78 CSNK2A1 (0.45) L3MBTL1ALDH1A1GAATP53MEN1
SCHEMBL1531081 0.77 CSNK2A1 (0.41) TSHRTDP1ALDH1A1GAALMNA
SCHEMBL5844789 0.77 L3MBTL1 (0.44) TDP1L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL5842676 0.76 XDH (0.41) XDH
SCHEMBL7931498 0.75 SLC2A1 (0.33)
SCHEMBL718547 0.74 NPC1 (0.41) L3MBTL1ALDH1A1GAALMNATP53
SCHEMBL1531130 0.73 LMNA (0.42) TSHRLMNAMEN1KMT2AADORA3
SCHEMBL6594937 0.73 ALDH1A1 (0.33) TDP1ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012041-B2 Phenylpyridazinones BAYER AG (DE) 2006-03-14 US disclosed
EP-1120411-B1 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides BAYER CROPSCIENCE AG (DE) 2004-09-22 EP disclosed
US-6743755-B2 HERBICIDAL COMPOSITION WHICH HAS A CONTENT OF AT LEAST ONE N-ARYL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OF THE GENERAL METHOD OF COMBATING UNDESIRABLE PLANTS WHICH COMPRISES ALLOWING AN N-ARYL NITROGEN-CONTAINING HETEROCYCLIC BAYER AKTIENGESELLSCHAFT (DE) 2004-06-01 US disclosed
CN-1138762-C Phenylpyridazinones 2004-02-18 CN disclosed
EP-0832072-B1 PHENYLPYRIDAZINONES BAYER CROPSCIENCE AG (DE) 2003-09-24 EP disclosed
US-6551963-B1 For controlling unwanted vegetation BAYER AKTIENGESELLSCHAFT (DE) 2003-04-22 US disclosed
EP-1120411-A2 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides BAYER AG (DE) 2001-08-01 EP disclosed
WO-2001009087-A1 SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-08 WO disclosed
US-6162765-A Substituted N-aryl nitrogen-containing heterocyclic compounds BAYER AKTIENGESELLSCHAFT (DE) 2000-12-19 US disclosed
CN-1192208-A Phenylpyridazinones BAYER AG (DE) 1998-09-02 CN disclosed
EP-0832072-A1 PHENYLPYRIDAZINONES BAYER AG (DE) 1998-04-01 EP disclosed
EP-0797573-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AG (DE) 1997-10-01 EP disclosed
WO-1997026248-A1 SUBSTITUTED N-ARYL NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-07-24 WO disclosed
WO-1997005117-A1 SUBSTITUTED 1-PHENYLURACIL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-02-13 WO disclosed
WO-1996039392-A1 PHENYLPYRIDAZINONES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-12 WO disclosed
WO-1996018618-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1996-06-20 WO disclosed