SCHEMBL5843599

SCHEMBL5843599

CCCCCCOc1ccc(OCCCCCC)c(S(=O)(=O)C(=[N+]=[N-])C(=O)c2ccc3ccccc3c2)c1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRA P10827 3/20 0.43
THRB P10828 2/20 0.41
MTNR1A P48039 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
PLA2G4B P0C869 1/20 0.39
PTPN11 Q06124 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843907 0.93 THRA (0.43) THRAMTNR1ATP53TSHRPLA2G4B
SCHEMBL5861995 0.92 THRA (0.40) THRATHRBCNR1CNR2
SCHEMBL5862358 0.91 THRA (0.39) THRATHRBCNR1CNR2
SCHEMBL5862941 0.90 PTPN1 (0.40) THRATHRBCNR1CNR2
SCHEMBL5861673 0.90 RAPGEF3 (0.38) THRATHRBCNR1CNR2
SCHEMBL5845465 0.89 PLA2G4B (0.43) TP53TSHRPLA2G4BPTPN11
SCHEMBL5861730 0.89 PTPN1 (0.39) THRATHRBCNR1CNR2
SCHEMBL5843423 0.89 CNR1 (0.39) THRATHRBCNR1CNR2
SCHEMBL5862983 0.88 ENPP1 (0.39) THRATHRBCNR1CNR2
SCHEMBL5843961 0.87 CNR1 (0.37) THRATHRBCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7101651-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO.,LTD. (JP) 2006-09-05 US disclosed
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process VEGFA, POLL, PIM3 THRA 1957/4885THRB 3044/4885MTNR1A 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.