SCHEMBL5862983

SCHEMBL5862983

CCCCOc1ccc(C(C)(C)C)cc1S(=O)(=O)C(=[N+]=[N-])C(=O)c1ccc2ccccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 1/20 0.39
NR1I2 O75469 3/20 0.36
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
PTPN1 P18031 1/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5861730 0.97 PTPN1 (0.39) ENPP1NR1I2PTPN1CNR1CNR2
SCHEMBL5862941 0.96 PTPN1 (0.40) ENPP1PTPN1CNR1CNR2THRA
SCHEMBL5862002 0.89 NR1I2 (0.41) NR1I2PPARGPPARAGAATDP1
SCHEMBL5861673 0.89 RAPGEF3 (0.38) PPARGPPARAGAATDP1L3MBTL1
SCHEMBL5843599 0.88 THRA (0.43) CNR1CNR2THRATHRB
SCHEMBL5862942 0.87 PTPN11 (0.39) NR1I2GAAPTGDR2THRATHRB
SCHEMBL5862358 0.86 THRA (0.39) PTPN1CNR1CNR2HDAC3HDAC1
SCHEMBL5862965 0.86 PTPN11 (0.41) NR1I2GAATHRATHRB
SCHEMBL5861995 0.85 THRA (0.40) PPARGPPARAPTPN1CNR1CNR2
SCHEMBL5843423 0.82 CNR1 (0.39) PPARGPPARAPTPN1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109311-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process POLL, VEGFA, PIM3 ENPP1 2571/4885NR1I2 4388/4885PPARG 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.