SCHEMBL5861673

SCHEMBL5861673

CCCCOc1ccc(C)cc1S(=O)(=O)C(=[N+]=[N-])C(=O)c1ccc2ccccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF3 O95398 1/20 0.38
GAA P10253 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX12 P18054 1/20 0.36
ENPP2 Q13822 1/20 0.36
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
WDR5 P61964 1/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5862358 0.97 THRA (0.39) RAPGEF3CNR1CNR2HDAC3HDAC1
SCHEMBL5861995 0.96 THRA (0.40) CNR1CNR2ALDH1A1PPARGPPARA
SCHEMBL5843599 0.90 THRA (0.43) CNR1CNR2THRATHRB
SCHEMBL5862526 0.89 WDR5 (0.40) GAAL3MBTL1CES2CES1PPARG
SCHEMBL5862983 0.89 ENPP1 (0.39) GAATDP1L3MBTL1CNR1CNR2
SCHEMBL5862927 0.86 PTPN11 (0.40) GAAL3MBTL1ALDH1A1WDR5THRA
SCHEMBL5861730 0.86 PTPN1 (0.39) CNR1CNR2HDAC3HDAC1HDAC2
SCHEMBL5862941 0.85 PTPN1 (0.40) CNR1CNR2ALDH1A1THRATHRB
SCHEMBL5862527 0.85 PTPN11 (0.42) CES2CES1ALDH1A1WDR5THRA
SCHEMBL5843961 0.84 CNR1 (0.37) CNR1CNR2HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109311-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process POLL, VEGFA, PIM3 RAPGEF3 2776/4885GAA 1960/4885TDP1 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.