Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177923 | 0.90 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL4187497 | 0.78 | ALDH1A1 (0.44) | PTGS2 | |
| SCHEMBL4184036 | 0.74 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL4189726 | 0.74 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL4187448 | 0.73 | PTGS2 (0.41) | PTGS2METAP2 | |
| SCHEMBL4179892 | 0.73 | TGFBR1 (0.34) | — | |
| SCHEMBL4192577 | 0.70 | PTGS2 (0.39) | PTGS2METAP2 | |
| SCHEMBL4188086 | 0.70 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL7817113 | 0.66 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL4180686 | 0.62 | PTGS2 (0.41) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115591-B2 | Pyridazinone compounds as cyclooxygenase [COX] 2 inhibitorsfor gastrointestinal disorders | ABBOTT LABORATORIES (US) | 2006-10-03 | — | — | US | disclosed |
| US-20040158064-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158064-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | PTGS2 3/4885METAP2 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.